abstract：:Reversible protein phosphorylation, regulated by protein kinases and phosphatases, mediates a switch between protein activity and cellular pathways that contribute to a large number of cellular processes. The Mycobacterium tuberculosis genome encodes 11 Serine/Threonine kinases (STPKs) which show close homology to euk...

journal_title：Frontiers in microbiology

authors： Fortuin S,Tomazella GG,Nagaraj N,Sampson SL,Gey van Pittius NC,Soares NC,Wiker HG,de Souza GA,Warren RM

更新日期：2015-02-10 00:00:00

abstract：:The virulence factor PgtE is an outer membrane protease (omptin) of the zoonotic pathogen Salmonella enterica that causes diseases ranging from gastroenteritis to severe enteric fever. It is surface exposed in bacteria that have a short-chain, i.e., rough LPS, as observed e.g., in bacteria residing inside macrophages ...

journal_title：Frontiers in microbiology

authors： Riva R,Korhonen TK,Meri S

更新日期：2015-02-06 00:00:00

abstract：:Biological disease models can be difficult and costly to develop and use on a routine basis. Particularly, in vivo lung infection models performed to study lung pathologies use to be laborious, demand a great time and commonly are associated with ethical issues. When infections in experimental animals are used, they n...

journal_title：Frontiers in microbiology

authors： López Hernández Y,Yero D,Pinos-Rodríguez JM,Gibert I

更新日期：2015-02-04 00:00:00

abstract：:During the summer months, wet (hyporheic) soils associated with ephemeral streams and lake edges in the Antarctic Dry Valleys (DVs) become hotspots of biological activity and are hypothesized to be an important source of carbon and nitrogen for arid DV soils. Recent research in the DV has focused on the geochemistry a...

journal_title：Frontiers in microbiology

authors： Niederberger TD,Sohm JA,Gunderson TE,Parker AE,Tirindelli J,Capone DG,Carpenter EJ,Cary SC

更新日期：2015-01-28 00:00:00

abstract：:Historically, vaccines have been designed to mimic the immunity induced by natural exposure to the target pathogen, but this approach has not been effective for any parasitic pathogen of humans or complex pathogens that cause chronic disease in humans, such as Plasmodium. Despite intense efforts by many laboratories a...

journal_title：Frontiers in microbiology

authors： Proietti C,Doolan DL

更新日期：2015-01-22 00:00:00

abstract：:A moderately halotolerant Streptomyces strain, designated JAJ13 was characterized and a culture medium was statistically optimized to improve its antibacterial activity. Based on the phenotypic and molecular characteristics, strain JAJ13 was identified as a moderately halotolerant Streptomyces sp. JAJ13. Novelty of th...

journal_title：Frontiers in microbiology

authors： Rajeswari P,Jose PA,Amiya R,Jebakumar SR

更新日期：2015-01-21 00:00:00

abstract：:Little is known about the importance and/or mechanisms of biological mineral oxidation in sediments, partially due to the difficulties associated with culturing mineral-oxidizing microbes. We demonstrate that electrochemical enrichment is a feasible approach for isolation of microbes capable of gaining electrons from ...

journal_title：Frontiers in microbiology

authors： Rowe AR,Chellamuthu P,Lam B,Okamoto A,Nealson KH

更新日期：2015-01-14 00:00:00

abstract：:We studied the resident (16S rDNA) and the active (16S rRNA) members of soil archaeal and bacterial communities during rice plant development by sampling three growth stages (vegetative, reproductive and maturity) under field conditions. Additionally, the microbial community was investigated in two non-flooded fields ...

journal_title：Frontiers in microbiology

authors： Breidenbach B,Conrad R

更新日期：2015-01-08 00:00:00

abstract：:The meals from many oilseed crops have potential for biofumigation due to their release of biocidal compounds such as isothiocyanates (ITCs). Various ITCs are known to inhibit numerous pathogens; however, much less is known about how the soil microbial community responds to the different types of ITCs released from oi...

journal_title：Frontiers in microbiology

authors： Hu P,Hollister EB,Somenahally AC,Hons FM,Gentry TJ

更新日期：2015-01-07 00:00:00

abstract：:Replication of the bacterial chromosome initiates at a single origin of replication that is called oriC. This occurs via the concerted action of numerous proteins, including DnaA, which acts as an initiator. The origin sequences vary across species, but all bacterial oriCs contain the information necessary to guide as...

journal_title：Frontiers in microbiology

authors： Wolański M,Donczew R,Zawilak-Pawlik A,Zakrzewska-Czerwińska J

更新日期：2015-01-06 00:00:00

abstract：:Historically filamentous bacteriophage have been known to be the workhorse of phage display due to their ability to link genotype to phenotype. More recently, the filamentous phage scaffold has proven to be powerful outside the realm of phage display technology in fields such as molecular imaging, cancer research and ...

journal_title：Frontiers in microbiology

authors： Bernard JM,Francis MB

更新日期：2014-12-23 00:00:00

abstract：:Legionella pneumophila is a natural intracellular bacterial parasite of free-living freshwater protozoa and an accidental human pathogen that causes Legionnaires' disease. L. pneumophila differentiates, and does it in style. Recent experimental data on L. pneumophila's differentiation point at the existence of a compl...

journal_title：Frontiers in microbiology

authors： Robertson P,Abdelhady H,Garduño RA

更新日期：2014-12-22 00:00:00

abstract：:Climate change is affecting the amount and complexity of plant inputs to tropical forest soils. This is likely to influence the carbon (C) balance of these ecosystems by altering decomposition processes e.g., "positive priming effects" that accelerate soil organic matter mineralization. However, the mechanisms determi...

journal_title：Frontiers in microbiology

authors： Whitaker J,Ostle N,McNamara NP,Nottingham AT,Stott AW,Bardgett RD,Salinas N,Ccahuana AJ,Meir P

更新日期：2014-12-18 00:00:00

abstract：:Through the expression of the accessory gene regulator quorum sensing cascade, Staphylococcus aureus is able to produce an extensive array of enzymes, hemolysins and immunomodulators essential to its ability to spread through the host tissues and cause disease. Many have argued for the discovery and development of quo...

journal_title：Frontiers in microbiology

authors： Quave CL,Horswill AR

更新日期：2014-12-12 00:00:00

abstract：:The seasonal melting of ice entombed cryoconite holes on McMurdo Dry Valley glaciers provides oases for life in the harsh environmental conditions of the polar desert where surface air temperatures only occasionally exceed 0°C during the Austral summer. Here we follow temporal changes in cryoconite hole biogeochemistr...

journal_title：Frontiers in microbiology

authors： Telling J,Anesio AM,Tranter M,Fountain AG,Nylen T,Hawkings J,Singh VB,Kaur P,Musilova M,Wadham JL

更新日期：2014-12-11 00:00:00

abstract：:In the present study, long-term organic and conventional managements were compared at the experimental field of Monsampolo del Tronto (Marche region, Italy) with the aim of investigating soil chemical fertility and microbial community structure. A polyphasic approach, combining soil fertility indicators with microbiol...

journal_title：Frontiers in microbiology

authors： Stagnari F,Perpetuini G,Tofalo R,Campanelli G,Leteo F,Della Vella U,Schirone M,Suzzi G,Pisante M

更新日期：2014-12-10 00:00:00

abstract：:Hepatitis C virus (HCV) infection has become a global public health burden costing billions of dollars in health care annually. Even with rapidly advancing scientific technologies this disease still poses a significant threat due to a lack of vaccines and affordable treatment options. The immune correlates of protecti...

journal_title：Frontiers in microbiology

authors： Manickam C,Reeves RK

更新日期：2014-12-08 00:00:00

abstract：:Protein export in bacteria is facilitated by the canonical SecB chaperone, which binds to unfolded precursor proteins, maintains them in a translocation competent state and specifically cooperates with the translocase motor SecA to ensure their proper targeting to the Sec translocon at the cytoplasmic membrane. Beside...

journal_title：Frontiers in microbiology

authors： Sala A,Bordes P,Genevaux P

更新日期：2014-12-05 00:00:00

abstract：:Sterile attenuation of Plasmodium parasites at the liver-stage either by irradiation or genetic modification, or at the blood-stage by chemoprophylaxis, has been shown to induce immune responses that can protect against subsequent wild-type infection. However, following certain interventions, parasite attenuation can ...

journal_title：Frontiers in microbiology

authors： Fernandes P,Frank R,Lewis MD,Mueller AK

更新日期：2014-12-02 00:00:00

abstract：:A vital function of the cell membrane in all living organism is to maintain the membrane permeability barrier and fluidity. The composition of the phospholipid bilayer is distinct in archaea when compared to bacteria and eukarya. In archaea, isoprenoid hydrocarbon side chains are linked via an ether bond to the sn-gly...

journal_title：Frontiers in microbiology

authors： Jain S,Caforio A,Driessen AJ

更新日期：2014-11-26 00:00:00

abstract：:The majority of caves are formed within limestone rock and hence our understanding of cave microbiology comes from carbonate-buffered systems. In this paper, we describe the microbial diversity of Roraima Sur Cave (RSC), an orthoquartzite (SiO4) cave within Roraima Tepui, Venezuela. The cave contains a high level of m...

journal_title：Frontiers in microbiology

authors： Barton HA,Giarrizzo JG,Suarez P,Robertson CE,Broering MJ,Banks ED,Vaishampayan PA,Venkateswaran K

更新日期：2014-11-26 00:00:00

abstract：:Bacillus amyloliquefaciens SQR9 exhibited predominantly antagonistic activities against a broad range of soilborne pathogens. The fungi-induced SQR9 extracts possess stronger antifungal activities compared with SQR9 monoculture extracts. To investigate how SQR9 fine-tunes lipopeptides (LPs) and a siderophore bacilliba...

journal_title：Frontiers in microbiology

authors： Li B,Li Q,Xu Z,Zhang N,Shen Q,Zhang R

更新日期：2014-11-21 00:00:00

abstract：:Antibodies are capable of blocking infection of the liver by Plasmodium sporozoites. Accordingly the induction of anti-sporozoite antibodies is a major aim of various vaccine approaches to malaria. In recent years our knowledge of the specificity and quantities of antibodies required for protection has been greatly ex...

journal_title：Frontiers in microbiology

authors： Dups JN,Pepper M,Cockburn IA

更新日期：2014-11-18 00:00:00

abstract：:The survival of Shewanella oneidensis MR-1 at up to 1500 MPa was investigated by laboratory studies involving exposure to high pressure followed by evaluation of survivors as the number (N) of colony forming units (CFU) that could be cultured following recovery to ambient conditions. Exposing the wild type (WT) bacter...

journal_title：Frontiers in microbiology

authors： Hazael R,Foglia F,Kardzhaliyska L,Daniel I,Meersman F,McMillan P

更新日期：2014-11-17 00:00:00

abstract：:Cobamides are a family of enzyme cofactors that include vitamin B12 (cobalamin) and are produced solely by prokaryotes. Structural variability in the lower axial ligand has been observed in cobamides produced by diverse organisms. Of the three classes of lower ligands, the benzimidazoles are uniquely found in cobamide...

journal_title：Frontiers in microbiology

authors： Crofts TS,Men Y,Alvarez-Cohen L,Taga ME

更新日期：2014-11-13 00:00:00

abstract：:Extremely cold environments are a challenge for all organisms. They are mostly inhabited by psychrophilic and psychrotolerant bacteria, which employ various strategies to cope with the cold. Such harsh environments are often highly vulnerable to the influence of external factors and may undergo frequent dynamic change...

journal_title：Frontiers in microbiology

authors： Dziewit L,Bartosik D

更新日期：2014-11-06 00:00:00

abstract：:The mycorrhizal symbiosis between soil fungi and plant roots is a ubiquitous mutualism that plays key roles in plant nutrition, soil health, and carbon cycling. The symbiosis evolved repeatedly and independently as multiple morphotypes [e.g., arbuscular mycorrhizae (AM), ectomycorrhizal (ECM)] in multiple fungal clade...

journal_title：Frontiers in microbiology

authors： Kuo A,Kohler A,Martin FM,Grigoriev IV

更新日期：2014-11-04 00:00:00

abstract：:Fungi are prominent components of most terrestrial ecosystems, both in terms of biomass and ecosystem functioning, but the hyper-diverse nature of most communities has obscured the search for unifying principles governing community organization. In particular, unlike plants and animals, observational studies provide l...

journal_title：Frontiers in microbiology

authors： Crowther TW,Maynard DS,Crowther TR,Peccia J,Smith JR,Bradford MA

更新日期：2014-10-31 00:00:00

abstract：:Sponges that harbor microalgal or, cyanobacterial symbionts may benefit from photosynthetically derived carbohydrates, which are rich in carbon but devoid of nitrogen, and may therefore encounter nitrogen limitation. Diazotrophic communities associated with two Caribbean sponges, Ircinia strobilina and Mycale laxissim...

journal_title：Frontiers in microbiology

authors： Zhang F,Vicente J,Hill RT

更新日期：2014-10-28 00:00:00

abstract：:The increasing prevalence of hospital and community-acquired infections caused by multidrug-resistant (MDR) bacterial pathogens is limiting the options for effective antibiotic therapy. Moreover, this alarming spread of antimicrobial resistance has not been paralleled by the development of novel antimicrobials. Resist...

journal_title：Frontiers in microbiology

authors： Cassir N,Rolain JM,Brouqui P

更新日期：2014-10-20 00:00:00

abstract：:Label-free bacterial colony phenotyping technology called BARDOT (Bacterial Rapid Detection using Optical scattering Technology) provided successful classification of several different bacteria at the genus, species, and serovar level. Recent experiments with colonies of Bacillus species provided strikingly different ...

journal_title：Frontiers in microbiology

authors： Kim H,Singh AK,Bhunia AK,Bae E

更新日期：2014-10-14 00:00:00

abstract：:Emergence of multidrug-resistant Salmonella typhimurium strains, especially the ACSSuT and nalidixic acid R types, has significantly compromised the effectiveness of current strategies to control Salmonella infections, resulting in increased morbidity and mortality. Clinical S. typhimurium isolates recovered in Hong K...

journal_title：Frontiers in microbiology

authors： Wong MH,Chan EW,Liu LZ,Chen S

更新日期：2014-10-02 00:00:00

abstract：:Microbial associations are integral to all eukaryotes. Mutualism, the interaction of two species for the benefit of both, is an important aspect of microbial associations, with evidence that multicellular organisms in particular benefit from microbes. However, the microbe's perspective has largely been ignored, and it...

journal_title：Frontiers in microbiology

authors： Garcia JR,Gerardo NM

更新日期：2014-09-26 00:00:00

abstract：OBJECTIVE:Approximately 5% of women suffer from recurrent vulvovaginal candidiasis (RVVC). It has been hypothesized that genetic factors play an important role in the susceptibility to RVVC. The aim of this study was to assess the effect of genetic variants of genes encoding for pattern recognition receptors (PRRs) on ...

journal_title：Frontiers in microbiology

authors： Rosentul DC,Delsing CE,Jaeger M,Plantinga TS,Oosting M,Costantini I,Venselaar H,Joosten LA,van der Meer JW,Dupont B,Kullberg BJ,Sobel JD,Netea MG

更新日期：2014-09-23 00:00:00

abstract：:Research in the deep terrestrial biosphere is driven by interest in novel biodiversity and metabolisms, biogeochemical cycling, and the impact of human activities on this ecosystem. As this interest continues to grow, it is important to ensure that when subsurface investigations are proposed, materials recovered from ...

journal_title：Frontiers in microbiology

authors： Wilkins MJ,Daly RA,Mouser PJ,Trexler R,Sharma S,Cole DR,Wrighton KC,Biddle JF,Denis EH,Fredrickson JK,Kieft TL,Onstott TC,Peterson L,Pfiffner SM,Phelps TJ,Schrenk MO

更新日期：2014-09-12 00:00:00

abstract：:Microbial processes such as nitrification and anaerobic ammonium oxidation (anammox) are important for nitrogen cycling in marine sediments. Seasonal variations of archaeal and bacterial ammonia oxidizers (AOA and AOB) and anammox bacteria, as well as the environmental factors affecting these groups, are not well stud...

journal_title：Frontiers in microbiology

authors： Lipsewers YA,Bale NJ,Hopmans EC,Schouten S,Sinninghe Damsté JS,Villanueva L

更新日期：2014-09-05 00:00:00

abstract：:In bacteria, transfer-messenger RNA (tmRNA) and SmpB comprise the most common and effective system for rescuing stalled ribosomes. Ribosomes stall on mRNA transcripts lacking stop codons and are rescued as the defective mRNA is swapped for the tmRNA template in a process known as trans-translation. The tmRNA-SmpB comp...

journal_title：Frontiers in microbiology

authors： Miller MR,Buskirk AR

更新日期：2014-09-02 00:00:00

abstract：:DNA polymerase is a ubiquitous enzyme that synthesizes complementary DNA strands according to the template DNA in living cells. Multiple enzymes have been identified from each organism, and the shared functions of these enzymes have been investigated. In addition to their fundamental role in maintaining genome integri...

journal_title：Frontiers in microbiology

authors： Ishino S,Ishino Y

更新日期：2014-08-29 00:00:00

abstract：:The structure and function of the plant microbiome is driven by plant species and prevailing environmental conditions. Effectuated by breeding efforts, modern crops diverge genetically and phenotypically from their wild relatives but little is known about consequences for the associated microbiota. Therefore, we studi...

journal_title：Frontiers in microbiology

authors： Zachow C,Müller H,Tilcher R,Berg G

更新日期：2014-08-26 00:00:00

abstract：:An actinomycetes strain designated as MN 2(6) was isolated from the solitary wasp mud nest. The isolate was identified using polyphasic taxonomy. It produced the extensive branched brown substrate and white aerial hyphae that changed into grayish black. The aerial mycelia produced the spiral spore chains with rugose s...

journal_title：Frontiers in microbiology

authors： Kumar V,Naik B,Gusain O,Bisht GS

更新日期：2014-08-21 00:00:00